Vol. 17 (2019)

Review

• Evolving Targets for Heart Failure: the Journey so far

  Giuseppe Rosano

  • Rosano-589

• The Clinical Problem: Heart Failure Syndromes and their Epidemiology

  Marta Kaluzna-Oleksy, Ewa Jankowska

  • Kałuzna-Oleksy-591

• The Scientific Targets: the Myocardium, the Vasculature and the Body’s Response to Heart Failure

  Rafael Vidal-Pérez, Ewa Jankowska

  • Vidal-Pérez-593

• Clinical Trial Design, Endpoints and Regulatory Considerations in Heart Failure

  Giuseppe Rosano

  • Rosano-595

• Modulation of Cardiac Metabolism in Heart Failure

  Giuseppe Rosano, Andrew Coats

  • Rosano+Coats-597

• If Channel Inhibition - Ivabradine for the Treatment of Heart Failure

  Giuseppe Rosano, Cristiana Vitale

  • Rosano+Vitale-599

• Combined RAAS and NEP Inhibition

  Giuseppe Vergaro, Marco Metra

  • Vergaro-601

• Mineralocorticoid Receptor Antagonists

  Ilaria Spoletini, Giuseppe Rosano

  • Spoletini-603

• Vasopressin Receptor Antagonists (Vaptans) in Heart Failure

  Piotr Lipiec, Marco Metra

  • Lipiec-605

• Phosphodiesterase Inhibitors

  Rui Plácido, Mitja Lainscak

  • Plácido-607