Takotsubo Syndrome and Cerebral Cardioembolism: Case Report to Redefine the Short-term Prognosis
DOI:
https://doi.org/10.17987/icfj.v4i0.154Keywords:
Takotsubo, stroke, cardiac embolismAbstract
Takotsubo cardiomyopathy is characterized by transient hypo-kinesis of the left ventricular apex or midventricular segments, without significant stenosis affecting coronary arteries. This cardiomyopathy is well known to be related to cerebral infarction, although scarce data describe the real timing of this adverse event.
We report the case of a 69-year-old woman who experienced Takotsubo cardiomyopathy, and developed cardiogenic cerebral embolism on the fourth day from the onset of symptoms.
Takotsubo patients could be effectively at high risk for stroke; thus, we should pay attention to rule out ventricular thrombosis, consider immediately anticoagulant therapy, and revise Takotsubo prognosis because its complications.References
Kurisu S, Kihara Y. Tako-tsubo cardiomyopathy: clinical presentation and underlying mechanism. J Cardiol. 2012 Dec;60(6):429-37. doi: 10.1016/j.jjcc.2012.06.015. Epub 2012 Oct 15.
De Boer D, Ring C, Wood M, Ford C, Jessney N, McIntyre D, Carroll D. Timecourse and mechanisms of mental stress-induced changes and their recovery: hematocrit, colloid osmotic pressure, whole blood viscosity, coagulation times, and hemodynamic activity. Psychophysiology 2007;44:639e649.
Ajmani RS, Fleg JL, Demehin AA, Wright JG, O’Connor F, Heim JM, Tarien E, Rifkind JM. Oxidative stress and hemorheological changes induced by acute treadmill exercise. Clin Hemorheol Microcirc 2003;28:29e40.
Bielecka-Dabrowa A, Mikhailidis DP, Hannam S, Rysz J, Michalska M, Akashi YJ, Banach M. Takotsubo cardiomyopathy—the current state of knowledge. Int J Cardiol 2010;142:120e125.
Cecchi E, Parodi G, Giglioli C, Passantino S, Bandinelli B, Liotta AA, Bellandi B, Cioni G, Costanzo M, Abbate R, Gensini GF, Antoniucci D, Mannini L.Stress-induced hyperviscosity in the pathophysiology of takotsubo cardiomyopathy.Am J Cardiol. 2013 May 15;111(10):1523-9. doi: 10.1016/j.amjcard.2013.01.304.
De Gregorio C, Grimaldi P, Lentini C. Left ventricular thrombus formation and cardioembolic complications in patients with Takotsubo-like syndrome: a systematic re- view. Int J Cardiol 2008;131:18-24.
Yoshimura S, Toyoda K, Ohara T, et al. Takotsubo cardio- myopathy in acute ischemic stroke. AnnNeurol 2008; 64:547-554.
Jabiri MZ, Mazighi M, Meimoun P, et al. Tako-tsubo syndrome: a cardioembolic cause of brain infarction. CerebrovascDis 2010;29:309-310.
Kim SM, Aikat S, Bailey A, White M. Takotsubo cardiomyopathy as a source of cardioembolic cerebral infarction. BMJ Case Rep. 2012 Sep 21;2012. pii: bcr2012006835. doi: 10.1136/bcr-2012-006835.
Matsuzono K, Ikeda Y, Deguchi S, Yamashita T, Kurata T, Deguchi K, Abe K. Cerebral embolic stroke after disappearing takotsubo cardiomyopathy. J Stroke Cerebrovasc Dis. 2013 Nov;22(8):e682-3. doi: 10.1016/j.jstrokecerebrovasdis.2013.07.022. Epub 2013 Aug 15.
Shewan LG, Coats AJS, Henein M. Requirements for ethical publishing in biomedical journals. International Cardiovascular Forum Journal 2015;2:2 DOI: 10.17987/icfj.v2i1.4
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