Unusual Etiology of Acute Myocardial Infarction – Factor V Leiden Mutation


  • Alghafek Almorraweh Al Bassel Heart Institute, Damascus, Syria.




The genetic defect of coagulation factor V known as factor V Leiden produces a resistance to degradation of factor V by activated protein C (APC) and that will increase the risk of venous thromboembolism. The data on arterial thrombosis and acute myocardial infarction associated with APC resistance are still not clearly defined.  We report a case of acute myocardial infarction in young patient with no cardiovascular risk factors  and the etiology of the myocardial infarction was defined as acute arterial thrombosis associated with factor V Leiden defect, without any significant coronary lesions. 



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